Session 3 | Tumor Evolution & Plasticity
Section outline
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Session 3 – 9/9/26 – Tumor Evolution & Plasticity
Question: Why aren’t cancer cells the same?
Topics covered in class:
o Clonal evolution;
o Cancer heterogeneity;
o Genetic vs non-genetic mechanisms;
o Cell states & Plasticity;
o Selection;
o Therapies as selective pressure;
Paper to discuss:
Chan et al., Nature (2026) — Critical role for a high-plasticity cell state in lung cancer.
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Students mustMark as done
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