Section outline

    • Students must
      Mark as done

      Guided paper discussions.

      Selected papers will include both preclinical (in vitro mechanistic data, in vivo treatment, patient-derived xenografts, etc) and clinical data.

      Paper discussions will include description of figure panels included in the article by the scholars, who will be called by the class lead to provide context, describe the results in each figure, discuss the interpretation and implications of the results, suggest additional experiments or controls that would expand the implications of the results, and criticize the methodology, presentation and description of the results in the paper. The main goal of this activity is to “act as peer-reviewers” and train critical thinking.

      The paper to be discussed in Session 4 is: 

      • MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition (Mollaoglu et al., Cancer Cell 2017, PMID: 28089889)


    • Paper for Session 4 File
      Students must
      Mark as done