Section outline

  • Paper discussions will include description of figure panels included in the article by the students, who will be called by the class lead to provide context, describe the results in each figure, discuss the interpretation and implications of the results, suggest additional experiments or controls that would expand the implications of the results, and criticize the methodology, presentation, and description of the results in the paper. The main goal of this activity is to “act as peer-reviewers” and train critical thinking.

    We will discuss the following paper:
    Dunbar AJ, Bowman RL et al. Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms. Cancer Discov. 2024 May 1;14(5):737-751. doi: 10.1158/2159-8290.CD-22-0952. PMID: 38230747; PMCID: PMC11061606.

    These lectures should be watched before the class. If you have any questions from these lectures, please, bring them to the in person class.