M390- Principles of Pharmacotherapy in Clinical and Translational Cancer Research- Fall 2022

Conducting safe, high-quality clinical research necessitates accounting for on- and off-target drug effects and how drugs reach those targets across a diverse cohort. Principal investigators must apply crucial pharmacotherapeutic concepts when designing clinical cancer research to ensure protocols direct efforts to manage intra- and inter-patient differences in drug exposure and maximize safety.

This course explores principles of pharmacotherapy as they relate to clinical cancer research, including pharmacokinetics, pharmacodynamics, pharmacogenomics, drug interactions, and considerations in special populations. The course’s intent is to provide investigators with a practical foundation for rational incorporation of these principles into research protocols.