Topic outline

  • Core Course : September 29, 2025 - October 10, 2025

    • September 29, 2025: 9:30-12:30 - Chromosome Structure

      • Instructor: John Maciejowski

        Teaching Fellow: Vivian Kuan


      • Please review prior to class.

    • September 30, 2025: 9:30-12:30 - Discussion

      • Instructor: Ashley Nichols

        Teaching Fellow: Vivian Kuan

      • Student Presenter: Faye Li

      • Student Presenter: Faye Li

      • Student Presenter: Faye Li

    • October 1, 2025: 9:30-12:30 - Making and Breaking Phosphodiester and Phosphoanhydride Bonds

      • Instructor: Stewart Shuman

        Teaching Fellow: Vivian Kuan

      • Please note - all students should read the paper beforehand and be ready to discuss as a group.

      • Please review prior to class.

    • October 2, 2025: 9:30-12:30 - Chromosome Replication

      • Instructor: Dirk Remus

        Teaching Fellow: Vivian Kuan

    • October 3, 2025: 9:30-12:30 - Chromosome Replication - Paper Discussion

      • Instructor: Dirk Remus

        Teaching Fellow: Vivian Kuan

      • Student Presenter: Magnus, Karina

      • Student Presenter: Magnus, Karina

      • Student Presenter: Magnus, Karina

      • Please review prior to class.

    • October 6, 2025: 10:00-1:00 - Linkage Analysis

      • Instructor: Scott Keeney

        Teaching Fellow: Vivian Kuan

      • Please read, but we will not discuss in class except briefly; for purposes of this lecture, the first four pages of the paper are relevant.  Whole class should read and be prepared to discuss.


      • Please review prior to class - document also has several additional reading titles not posted on Moodle.

    • October 7, 2025: 9:30-12:30 - Radiation as a Therapeutic Agent

      • Instructor: Simon Powell

        Teaching Fellow: Vivian Kuan

      • Student Presenter: McIlhenny, Lauren


      • Please review prior to class.

    • October 8, 2025: 10:00-1:00 - Meiotic Recombnation

      • Instructor: Scott Keeney

        Teaching Fellow: Vivian Kuan

      • Student Presenter: Mutaher, Mohammed

      • Student Presenter: Mutaher, Mohammed

      • Please review prior to class; contains additional readings not posted to Moodle.

    • October 9, 2025: 10:00-1:00 - Biochemical Mechanisms of Homologous Recombination

      • Instructor: Scott Keeney

        Teaching Fellow: Vivian Kuan

      • Student Presenter: Pope, Eleanor

      • Please review prior to class; contains additional readings not posted to Moodle.

    • October 10, 2025: 9:30-12:30 - Telomeres and Telomerase in Aging and Cancer

      • Instructor: Agnel Sfeir

        Teaching Fellow: Vivian Kuan

      • Student Presenter: Styers, Hannah

      • Student Presenter: Styers, Hannah

      • Please review prior to class.

    • October 10, 2025: 1:00-3:00 - Review Session

      • Instructor: Vivian Kuan

        Teaching Fellow: Vivian Kuan

  • Core Course - October 14, 2025 - October 24, 2025

    • October 14, 2025: 9:30-12:30 - DNA Repair

      • Instructor: Xiaolan Zhao

        Teaching Fellow: Clark Thomson

      • Student Presenter: Sussman, Carleigh

      • Please review prior to class.

    • October 15, 2025: 9:30-12:30 - DNA Damage Response

      • Instructor: John Petrini

        Teaching Fellow: Clark Thomson

      • Syllabus contains groups - please consult prior to class for prep.

        Student Presenter Group A: Jalwa Afroz
        Student Presenter Group B: Christina Volpe

      • Please review prior to class

    • October 16, 2025: 9:30-12:30 - The Mitochondrial-Nuclear Crosstalk in Eukaryotic Evolution and Disease

    • October 17, 2025: 9:30-12:30 - Epigenetics

    • October 20, 2025: 9:30-12:30 - Drug Discovery and Development

    • October 21, 2025: 9:30-12:30 - Transcription

      • Instructor: Iestyn Whitehouse

        Teaching Fellow: Clark Thomson


      • Student Presenter: Magnus, Karina
      • Please review prior to class.

    • October 22, 2025: 9:30-12:30 - mRNA - Beyond the Genetic Code

      • Instructor: Christine Mayr

        Teaching Fellow: Clark Thomson


      • Student Presenter: McIlhenny, Lauren

      • Student Presenter: McIlhenny, Lauren

      • Please review prior to class.

    • October 23, 2025: 9:30-12:30 - RNAi and miRNAs

      • Instructor: Eric Lai

        Teaching Fellow: Clark Thomson


      • Student Presenter: Mutaher, Mohammed

      • Student Presenter: Mutaher, Mohammed

      • Student Presenter: Mutaher, Mohammed

      • Please review prior to class.

    • October 24, 2025: 9:30-12:30 - Protein-Nucleic and Interactions

    • October 24, 2025: 1:00-3:00 - Review Session

      • Instructor: Clark Thomson

        Teaching Fellow: Clark Thomson


  • Core Course - October 27, 2025 - November 7, 2025

    • October 27, 2025: 9:30-12:30 - CRISPR-CAS

      • Instructor: Naama Aviram

        Teaching Fellow: Amin Sabet


      • Dr Aviram will lead the discussion

    • October 28, 2025: 9:30-12:30 - Protein Structure, Folding and Modification

      • Instructor: Stephen Long

        Teaching Fellow: Amin Sabet


      • Student Presenter: Sussman, Carleigh

      • Student Presenter: Sussman, Carleigh

      • Please review prior to class - there are important pre-session instructions!

    • October 29, 2025: 9:30-12:30 - Senior Student Presentation

      • Instructor: Jenna Snyder; Klavdija Krause; Clark Thomson

        Teaching Fellow: Amin Sabet


    • October 30, 2025: 9:30-12:30 - Cell Cycle

      • Instructor: Andy Koff

        Teaching Fellow: Amin Sabet

      • Student Presenter: Volpe, Christina

      • Student Presenter: Volpe, Christina

      • Student Presenter: Volpe, Christina

      • Please review prior to class.

    • October 31, 2025: 9:30-12:30 - Chromosome Segregation and Cell Division

      • Instructor: Prasad Jallepalli

        Teaching Fellow: Amin Sabet


      • Student Presenter: Afroz, Jalwa

    • November 3, 2025: 9:30-12:30 - Programmed Cell Death

    • November 4, 2025: 9:30-12:30 - Programmed Cell Death

      • Instructor: Xuejun Jiang

        Teaching Fellow: Amin Sabet


      • Student Presenter: Beattie, Kai

      • Student Presenter: Beattie, Kai

      • Please review prior to class.

    • November 5, 2025: 9:30-12:30 - Using Genetics and Omics Data to inform Human Diseases

      • Instructor: Kushal Dey

        Teaching Fellow: Amin Sabet


      • Student Presenter: Li, Faye

      • Student Presenter: Li, Faye

      • Please review prior to class.

    • November 6, 2025: 9:30-12:30 - Ion Channels

    • November 7, 2025: 9:30-12:30 - Intrinsically Disordered Regions (IDRs) of Proteins

    • November 7, 2025: 1:00-3:00 - Review Session

      • Instructor: Amin Sabet

        Teaching Fellow: Amin Sabet


  • Core Course - November 10, 2025 - November 25, 2025

    • November 10, 2025: 9:30-12:30 - Translation

      • Instructor: Heeseon An / Alban Ordureau

        Teaching Fellow: Yassmin Elbanna

      • Student Presenter: Mutaher, Mohammed

      • Student Presenter: Mutaher, Mohammed

      • Student Presenter: Mutaher, Mohammed

      • Please review syllabus prior to class.

    • November 11, 2025: 9:30-12:30 - Endocytosis

      • Instructor: Michael Overholtzer

        Teaching Fellow: Yassmin Elbanna


      • Student Presenter: Pope, Eleanor

      • Student Presenter: Pope, Eleanor

      • Student Presenter: Pope, Eleanor

      • Please review prior to class.

    • November 12, 2025: 9:30-12:30 - Elucidating Protein Function and Mechanism

      • Instructor: Melinda Diver

        Teaching Fellow: Yassmin Elbanna


      • Student Presenter: Styers, Hannah

      • Student Presenter: Styers, Hannah

      • Student Presenter: Styers, Hannah

      • Please review prior to class.

    • November 13, 2025: 9:30-12:30 - Cell Adhesion

      • Instructor: Michael Overholtzer and Zaza Gelashvili

        Teaching Fellow: Yassmin Elbanna


      • Student Presenter: Sussman, Carleigh


      • Student Presenter: Sussman, Carleigh

      • Student Presenter: Sussman, Carleigh

    • November 14, 2025: 9:30-12:30 - Nuclear Mechanotransduction

      • Instructor: Philipp Niethammer

        Teaching Fellow: Yassmin Elbanna


      • Student Presenter: Volpe, Christina

      • Student Presenter: Volpe, Christina

      • Please review prior to class.

    • November 17, 2025: 9:30-12:30 - Gene Expression Organization and Biomolecular Condensates

      • Instructor: Jessica Sheu-Gruttadauria

        Teaching Fellow: Yassmin Elbanna


      • Please review carefully the document - it contains both the groups for the courtroom-style activity and readings that give a starting point for the activity.  Please let me know if you have any questions.

        Group leaders are: Afroz, Jalwa and Beattie, Kai

    • November 18, 2025: 9:30-12:30 - Self-Organized Patterning: Principles, Mechanisms, and Applications

      • Instructor: Christopher Brittin

        Teaching Fellow: Yassmin Elbanna


      • Please read this paper prior to class.

      • Please review prior to class.

    • November 20, 2025: 9:30-12:30 - Mechanobiology

      • Instructor: Morgan Huse

        Teaching Fellow: Yassmin Elbanna


      • Student Presenter: Ahmed, Nibras

      • Student Presenter: Ahmed, Nibras

      • Please review prior to class.

    • November 21, 2025: 9:30-12:30 - The Path from "Eureka!" to a Living Drug: Translating a Stem Cell-Derived Product to the Clinic

      • Instructor: Mark Tomishima

        Teaching Fellow: Yassmin Elbanna


      • Student Presenter: Li, Faye

      • Student Presenter: Li, Faye

      • Please review prior to class.

    • November 24, 2025: 9:30-12:30 - Early Mammalian Development: from Preimplantation to Gastrulation

      • Instructor: Kat Hadjantonakis

        Teaching Fellow: Yassmin Elbanna


      • Student Group Leaders: Magnus, Karina/McIlhenny, Lauren

        Be ready to argue for and against the argument in the papers and what was done well, not well.

      • Student Presenters:

      • Student Presenters:

      • Please review syllabus prior to class.  Groups are listed here.

    • November 25, 2025: 9:30-12:30 - Developmental Oncology: Pathways, Mechanisms, and Therapeutic Insights

    • November 25, 2025: TBD - Review Session

      • Instructor: Yassmin Elbanna

        Teaching Fellow: Yassmin Elbanna


  • Core Course - December 1, 2025 - December 12, 2025

    • December 1, 2025: 9:30-12:30 - Cell Therapies

      • Instructor: Lorenz Studer

        Teaching Fellow: Monika Komza


    • December 2, 2025: 9:30-12:30 - Stem Cell Therapy Clinical Trials

      • Instructor: Viviane Tabar

        Teaching Fellow: Monika Komza


      • Student Presenter: Tarrab, Stephanie

      • Student Presenter: Tarrab, Stephanie

      • Please review prior to class.

    • December 2, 2025: 1:30-4:30 - Mitochondria

      • Instructor: Giovanni Manfredi (Cornell)

        Teaching Fellow: Monika Komza


      • Syllabus contains groups - please consult prior to class for prep.

        Student Presenter Group A: Mutaher, Mohammed
        Student Presenter Group B: Pope, Eleanor


      • Please consult prior to class.  Contains groups

    • December 3, 2025: 10:00-1:00 - Introduction to Developmental Biology: Pattern Formation and Morphogenesis

      • Instructor: Mary Baylies

        Teaching Fellow: Monika Komza


      • Student Presenter: Styers, Hannah

      • Student Presenter: Styers, Hannah

      • Please review prior to class.

    • December 4, 2025: 9:30-12:30 - Stem Cells from Early Mammalian Embryos & Stem Cell-Derived Embryo Models

      • Instructor: Kat Hadjantonakis

        Teaching Fellow: Monika Komza


      • Student Presenters: Sussman, Carleigh/Volpe CJ

        Be ready to argue for and against the argument in the papers and what was done well, not well.

      • Student Presenters: Sussman, Carleigh/Volpe CJ

        Be ready to argue for and against the argument in the papers and what was done well, not well.


      • Student presenters: Sussman, Carleigh/Volpe CJ

      • Student Presenters: Sussman, Carleigh/Volpe CJ

      • Please review syllabus prior to class.

    • December 5, 2025: 9:30-12:30 - Gastrulation in Drosophila

      • Instructor: Jennifer Zallen

        Teaching Fellow: Monika Komza


      • Student Presenter: Afroz, Jalwa

    • December 8, 2025: 9:30-12:30 - Notch Signaling in Development and Cancer

      • Instructor: Eric Lai

        Teaching Fellow: Monika Komza


      • Student Presenter: Ahmed, Nibras

      • Student Presenter: Ahmed, Nibras

      • Please review prior to class.

    • December 9, 2025: 10:00-1:00 - Crosstalk between Signaling Pathways

    • December 10, 2025: 10:00-1:00 - Organogenesis

      • Instructor: Mary Baylies

        Teaching Fellow: Monika Komza

      • Student Presenter: Beattie, Kai

      • Student Presenter: Beattie, Kai

      • Please review prior to class.

    • December 11, 2025: 9:30-12:30 - Lecture/Group Presentation/Project

      • Instructor: Philipp Niethammer / Daniel Nicholson

        Teaching Fellow: Monika Komza

    • December 12, 2025: 9:30-12:30 - Group Presentation/Project

      • Instructor: Philipp Niethammer / Daniel Nicholson

        Teaching Fellow: Monika Komza


    • December 12, 2025: TBD - Review Session

      • Instructor: Monika Komza

        Teaching Fellow: Monika Komza